Potency data for probe TP-024 and control TP-024n
No in vitro potency data available.
In cell potency
| Target name | Target information | Species | Assay description | TP-024 | TP-024n | Publication of assay conditions |
|---|---|---|---|---|---|---|
| GPR52 | GPR52 expressed CHO cell line | Homo sapiens | CHO-based cAMP assay (human) | EC50 = 93 nM | EC50 > 1 µM | PMID: 28433511 |
| GPR52 | GPR52 expressed CHO cell line | Mus musculus | CHO-based cAMP assay (mouse) | EC50 = 141 nM | ||
| GPR52 | GPR52 expressed CHO cell line | Rattus sp. | CHO-based cAMP assay (rat) | EC50 = 134 nM | ||
| GPR52 | Rattus sp. | cAMP increase in rat primary cultured striatal neurons | EC50 = 151 nM |