Donated Chemical Probes

Selectivity data for probe SR-302 and control SR-301

SR-302

Compound concentration: 10 µM

Receptor	HGNC target name	Inhibition [%] (Primary experimental value)
5-HT1B	HTR1B	10.94
5-HT1D	HTR1D	18.90
GABAA		31.94
5-HT1A	HTR1A	-18.95
Sigma 2	TMEM97	32.04
5-HT2A	HTR2A	3.03
5-HT2B	HTR2B	12.25
Alpha1A	ADRA1A	34.90
Alpha1B	ADRA1B	-15.00
Alpha1D	ADRA1D	6.47
Beta1	ADRB1	20.28
Beta2	ADRB2	16.32
D1	DRD1	-8.61
D3	DRD3	2.38
D5	DRD5	23.47
H1	HRH1	3.62
H2	HRH2	-15.09
H3	HRH3	0.32
H4	HRH4	-7.56
M1	CHRM1	28.42
M2	CHRM2	18.50
M3	CHRM3	20.58
M4	CHRM4	-2.24
M5	CHRM5	-25.53
NET	SLC6A2	3.00
GABA/PBR		13.23
5-HT1E	HTR1E	-16.87
5-HT2C	HTR2C	8.24
5-HT3	HTR3A	3.83
5-HT5A	HTR5A	3.10
5-HT6	HTR6	18.17
5-HT7A	HTR7	11.35
Alpha2A	ADRA2A	7.22
Alpha2B	ADRA2B	13.50
Alpha2C	ADRA2C	5.25
Beta3	ADRB3	-12.62
GABAA/BZP		15.80
D2	DRD2	7.14
D4	DRD4	3.78
DAT	SLC6A3	11.52
DOR	OPRD1	8.18
KOR	OPRK1	20.08
MOR	OPRM1	45.31
SERT	SLC6A4	19.80
Sigma 1	SIGMAR1	32.02

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Primary results are shown as '% Ctrl', i.e. the negative control (DMSO) is equal 100% control and the positive control (control compound) is equal 0% control. For compounds showing less than 50% of control in the primary screening assay, a Kd will be determined. Note: It cannot be excluded that 0 % control values are due to assay artefacts.

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Jump to control KinomeScan data

SR-302

HGNC target name	DiscoverX gene symbol of kinase	% Control	Compound Concentration [nM]
AAK1	AAK1	92.0	100
ABL1	ABL1-phosphorylated	61.0	100
ABL2	ABL2	56.0	100
ACVR1	ACVR1	70.0	100
ACVR1B	ACVR1B	96.0	100
ACVR2A	ACVR2A	100.0	100
ACVR2B	ACVR2B	100.0	100
ACVRL1	ACVRL1	96.0	100
COQ8A	ADCK3	100.0	100
COQ8B	ADCK4	100.0	100
AKT1	AKT1	100.0	100
AKT2	AKT2	93.0	100
AKT3	AKT3	100.0	100
ALK	ALK(L1196M)	94.0	100
PRKAA1	AMPK-alpha1	100.0	100
PRKAA2	AMPK-alpha2	79.0	100
ANKK1	ANKK1	92.0	100
NUAK1	ARK5	88.0	100
MAP3K5	ASK1	100.0	100
MAP3K6	ASK2	100.0	100
AURKA	AURKA	100.0	100
AURKB	AURKB	95.0	100
AURKC	AURKC	98.0	100
AXL	AXL	96.0	100
BMP2K	BIKE	92.0	100
BLK	BLK	100.0	100
BMPR1A	BMPR1A	94.0	100
BMPR1B	BMPR1B	100.0	100
BMPR2	BMPR2	100.0	100
BMX	BMX	100.0	100
BRAF	BRAF(V600E)	51.0	100
PTK6	BRK	81.0	100
BRSK1	BRSK1	72.0	100
BRSK2	BRSK2	100.0	100
BTK	BTK	100.0	100
BUB1	BUB1	100.0	100
CAMK1	CAMK1	100.0	100
PNCK	CAMK1B	77.0	100
CAMK1D	CAMK1D	88.0	100
CAMK1G	CAMK1G	84.0	100
CAMK2A	CAMK2A	100.0	100
CAMK2B	CAMK2B	100.0	100
CAMK2D	CAMK2D	84.0	100
CAMK2G	CAMK2G	86.0	100
CAMK4	CAMK4	94.0	100
CAMKK1	CAMKK1	84.0	100
CAMKK2	CAMKK2	88.0	100
CASK	CASK	100.0	100
CDK11B	CDC2L1	94.0	100
CDK11A	CDC2L2	100.0	100
CDK13	CDC2L5	61.0	100
CDK19	CDK11	100.0	100
CDK2	CDK2	88.0	100
CDK3	CDK3	100.0	100
CDK4	CDK4-cyclinD3	100.0	100
CDK5	CDK5	100.0	100
CDK7	CDK7	100.0	100
CDK8	CDK8	42.0	100
CDK9	CDK9	100.0	100
CDKL1	CDKL1	91.0	100
CDKL2	CDKL2	85.0	100
CDKL3	CDKL3	100.0	100
CDKL5	CDKL5	100.0	100
CHEK1	CHEK1	100.0	100
CHEK2	CHEK2	37.0	100
CIT	CIT	100.0	100
CLK1	CLK1	86.0	100
CLK2	CLK2	98.0	100
CLK3	CLK3	100.0	100
CLK4	CLK4	98.0	100
CSF1R	CSF1R-autoinhibited	100.0	100
CSK	CSK	100.0	100
CSNK1A1	CSNK1A1	100.0	100
CSNK1A1L	CSNK1A1L	99.0	100
CSNK1D	CSNK1D	84.0	100
CSNK1E	CSNK1E	93.0	100
CSNK1G1	CSNK1G1	100.0	100
CSNK1G2	CSNK1G2	70.0	100
CSNK1G3	CSNK1G3	100.0	100
CSNK2A1	CSNK2A1	100.0	100
CSNK2A2	CSNK2A2	100.0	100
MATK	CTK	100.0	100
DAPK1	DAPK1	88.0	100
DAPK2	DAPK2	94.0	100
DAPK3	DAPK3	90.0	100
DCLK1	DCAMKL1	99.0	100
DCLK2	DCAMKL2	100.0	100
DCLK3	DCAMKL3	97.0	100
DDR1	DDR1	0.1	100
DDR2	DDR2	0.0	100
MAP3K12	DLK	100.0	100
DMPK	DMPK	98.0	100
CDC42BPG	DMPK2	98.0	100
STK17A	DRAK1	100.0	100
STK17B	DRAK2	83.0	100
DYRK1A	DYRK1A	100.0	100
DYRK1B	DYRK1B	100.0	100
DYRK2	DYRK2	100.0	100
EGFR	EGFR(T790M)	100.0	100
EIF2AK1	EIF2AK1	91.0	100
EPHA1	EPHA1	93.0	100
EPHA2	EPHA2	100.0	100
EPHA3	EPHA3	97.0	100
EPHA4	EPHA4	98.0	100
EPHA5	EPHA5	100.0	100
EPHA6	EPHA6	100.0	100
EPHA7	EPHA7	96.0	100
EPHA8	EPHA8	89.0	100
EPHB1	EPHB1	89.0	100
EPHB2	EPHB2	100.0	100
EPHB3	EPHB3	87.0	100
EPHB4	EPHB4	97.0	100
EPHB6	EPHB6	98.0	100
ERBB2	ERBB2	100.0	100
ERBB3	ERBB3	83.0	100
ERBB4	ERBB4	95.0	100
MAPK3	ERK1	67.0	100
MAPK1	ERK2	100.0	100
MAPK6	ERK3	96.0	100
MAPK4	ERK4	100.0	100
MAPK7	ERK5	94.0	100
MAPK15	ERK8	100.0	100
ERN1	ERN1	100.0	100
PTK2	FAK	92.0	100
FER	FER	99.0	100
FES	FES	100.0	100
FGFR1	FGFR1	100.0	100
FGFR2	FGFR2	100.0	100
FGFR3	FGFR3(G697C)	86.0	100
FGFR4	FGFR4	100.0	100
FGR	FGR	87.0	100
FLT1	FLT1	100.0	100
FLT3	FLT3-autoinhibited	93.0	100
FLT4	FLT4	95.0	100
FRK	FRK	77.0	100
FYN	FYN	80.0	100
GAK	GAK	96.0	100
EIF2AK4	GCN2(Kin.Dom.2,S808G)	100.0	100
GRK1	GRK1	100.0	100
GRK2	GRK2	88.0	100
GRK3	GRK3	100.0	100
GRK4	GRK4	100.0	100
GRK7	GRK7	91.0	100
GSK3A	GSK3A	100.0	100
GSK3B	GSK3B	100.0	100
HASPIN	HASPIN	74.0	100
HCK	HCK	100.0	100
HIPK1	HIPK1	100.0	100
HIPK2	HIPK2	100.0	100
HIPK3	HIPK3	100.0	100
HIPK4	HIPK4	88.0	100
MAP4K1	HPK1	95.0	100
HUNK	HUNK	100.0	100
CILK1	ICK	100.0	100
IGF1R	IGF1R	73.0	100
CHUK	IKK-alpha	100.0	100
IKBKB	IKK-beta	100.0	100
IKBKE	IKK-epsilon	100.0	100
INSR	INSR	100.0	100
INSRR	INSRR	100.0	100
IRAK1	IRAK1	100.0	100
IRAK3	IRAK3	65.0	100
IRAK4	IRAK4	100.0	100
ITK	ITK	90.0	100
JAK1	JAK1(JH2domain-pseudokinase)	100.0	100
JAK2	JAK2(JH1domain-catalytic)	100.0	100
JAK3	JAK3(JH1domain-catalytic)	69.0	100
MAPK8	JNK1	100.0	100
MAPK9	JNK2	90.0	100
MAPK10	JNK3	85.0	100
KIT	KIT-autoinhibited	100.0	100
LATS1	LATS1	98.0	100
LATS2	LATS2	76.0	100
LCK	LCK	83.0	100
LIMK1	LIMK1	75.0	100
LIMK2	LIMK2	92.0	100
STK11	LKB1	51.0	100
STK10	LOK	100.0	100
LRRK2	LRRK2(G2019S)	100.0	100
LTK	LTK	100.0	100
LYN	LYN	100.0	100
MAP3K13	LZK	74.0	100
MAK	MAK	100.0	100
MAP3K1	MAP3K1	100.0	100
MAP3K15	MAP3K15	100.0	100
MAP3K2	MAP3K2	100.0	100
MAP3K3	MAP3K3	100.0	100
MAP3K4	MAP3K4	91.0	100
MAP4K2	MAP4K2	92.0	100
MAP4K3	MAP4K3	87.0	100
MAP4K4	MAP4K4	100.0	100
MAP4K5	MAP4K5	100.0	100
MAPKAPK2	MAPKAPK2	76.0	100
MAPKAPK5	MAPKAPK5	100.0	100
MARK1	MARK1	100.0	100
MARK2	MARK2	100.0	100
MARK3	MARK3	74.0	100
MARK4	MARK4	100.0	100
MAST1	MAST1	94.0	100
MAP2K1	MEK1	100.0	100
MAP2K2	MEK2	100.0	100
MAP2K3	MEK3	100.0	100
MAP2K4	MEK4	100.0	100
MAP2K5	MEK5	97.0	100
MAP2K6	MEK6	72.0	100
MELK	MELK	100.0	100
MERTK	MERTK	94.0	100
MET	MET(Y1235D)	99.0	100
MINK1	MINK	85.0	100
MAP2K7	MKK7	95.0	100
MKNK1	MKNK1	100.0	100
MKNK2	MKNK2	84.0	100
MYLK3	MLCK	88.0	100
MAP3K9	MLK1	65.0	100
MAP3K10	MLK2	100.0	100
MAP3K11	MLK3	100.0	100
CDC42BPA	MRCKA	100.0	100
CDC42BPB	MRCKB	100.0	100
STK4	MST1	100.0	100
MST1R	MST1R	100.0	100
STK3	MST2	88.0	100
STK24	MST3	95.0	100
STK26	MST4	100.0	100
MTOR	MTOR	100.0	100
MUSK	MUSK	91.0	100
MYLK	MYLK	100.0	100
MYLK2	MYLK2	90.0	100
MYLK4	MYLK4	63.0	100
MYO3A	MYO3A	99.0	100
MYO3B	MYO3B	89.0	100
STK38	NDR1	81.0	100
STK38L	NDR2	40.0	100
NEK1	NEK1	68.0	100
NEK10	NEK10	100.0	100
NEK11	NEK11	94.0	100
NEK2	NEK2	86.0	100
NEK3	NEK3	100.0	100
NEK4	NEK4	100.0	100
NEK5	NEK5	89.0	100
NEK6	NEK6	100.0	100
NEK7	NEK7	100.0	100
NEK9	NEK9	100.0	100
MAP3K14	NIK	100.0	100
NIM1K	NIM1	64.0	100
NLK	NLK	100.0	100
OXSR1	OSR1	94.0	100
MAPK14	p38-alpha	77.0	100
MAPK11	p38-beta	36.0	100
MAPK13	p38-delta	100.0	100
MAPK12	p38-gamma	100.0	100
PAK1	PAK1	82.0	100
PAK2	PAK2	93.0	100
PAK3	PAK3	100.0	100
PAK4	PAK4	100.0	100
PAK6	PAK6	100.0	100
PAK5	PAK7	97.0	100
CDK16	PCTK1	100.0	100
CDK17	PCTK2	80.0	100
CDK18	PCTK3	100.0	100
PDGFRA	PDGFRA	99.0	100
PDGFRB	PDGFRB	100.0	100
PDPK1	PDPK1	100.0	100
CDPK1	PFCDPK1(P.falciparum)	78.0	100
PK5	PFPK5(P.falciparum)	100.0	100
CDK15	PFTAIRE2	95.0	100
CDK14	PFTK1	100.0	100
PHKG1	PHKG1	68.0	100
PHKG2	PHKG2	100.0	100
PIK3C2B	PIK3C2B	100.0	100
PIK3C2G	PIK3C2G	100.0	100
PIK3CA	PIK3CA(Q546K)	90.0	100
PIK3CB	PIK3CB	96.0	100
PIK3CD	PIK3CD	67.0	100
PIK3CG	PIK3CG	96.0	100
PI4KB	PIK4CB	98.0	100
PIKFYVE	PIKFYVE	100.0	100
PIM1	PIM1	89.0	100
PIM2	PIM2	100.0	100
PIM3	PIM3	99.0	100
PIP5K1A	PIP5K1A	89.0	100
PIP5K1C	PIP5K1C	100.0	100
PIP4K2B	PIP5K2B	100.0	100
PIP4K2C	PIP5K2C	100.0	100
PRKACA	PKAC-alpha	100.0	100
PRKACB	PKAC-beta	100.0	100
PKMYT1	PKMYT1	100.0	100
PKN1	PKN1	72.0	100
PKN2	PKN2	100.0	100
PKNB	PKNB(M.tuberculosis)	100.0	100
PLK1	PLK1	100.0	100
PLK2	PLK2	100.0	100
PLK3	PLK3	96.0	100
PLK4	PLK4	100.0	100
PRKCD	PRKCD	100.0	100
PRKCE	PRKCE	83.0	100
PRKCH	PRKCH	95.0	100
PRKCI	PRKCI	94.0	100
PRKCQ	PRKCQ	97.0	100
PRKD1	PRKD1	93.0	100
PRKD2	PRKD2	100.0	100
PRKD3	PRKD3	90.0	100
PRKG1	PRKG1	100.0	100
PRKG2	PRKG2	82.0	100
EIF2AK2	PRKR	47.0	100
PRKX	PRKX	65.0	100
PRPF4B	PRP4	74.0	100
PTK2B	PYK2	100.0	100
SIK3	QSK	100.0	100
RAF1	RAF1	61.0	100
RET	RET(V804M)	100.0	100
RIOK1	RIOK1	73.0	100
RIOK2	RIOK2	100.0	100
RIOK3	RIOK3	97.0	100
RIPK1	RIPK1	88.0	100
RIPK2	RIPK2	30.0	100
RIPK4	RIPK4	92.0	100
DSTYK	RIPK5	100.0	100
ROCK1	ROCK1	100.0	100
ROCK2	ROCK2	100.0	100
ROS1	ROS1	100.0	100
RPS6KA4	RPS6KA4(Kin.Dom.2-C-terminal)	100.0	100
RPS6KA5	RPS6KA5(Kin.Dom.2-C-terminal)	35.0	100
RPS6KA1	RSK1(Kin.Dom.2-C-terminal)	92.0	100
RPS6KA3	RSK2(Kin.Dom.2-C-terminal)	100.0	100
RPS6KA2	RSK3(Kin.Dom.2-C-terminal)	94.0	100
RPS6KA6	RSK4(Kin.Dom.2-C-terminal)	82.0	100
RPS6KB1	S6K1	100.0	100
SBK1	SBK1	77.0	100
SGK1	SGK	100.0	100
SBK3	SgK110	66.0	100
SGK2	SGK2	100.0	100
SGK3	SGK3	74.0	100
SIK1	SIK	92.0	100
SIK2	SIK2	100.0	100
SLK	SLK	99.0	100
NUAK2	SNARK	100.0	100
SNRK	SNRK	69.0	100
SRC	SRC	100.0	100
SRMS	SRMS	71.0	100
SRPK1	SRPK1	74.0	100
SRPK2	SRPK2	83.0	100
SRPK3	SRPK3	100.0	100
STK16	STK16	100.0	100
STK33	STK33	100.0	100
STK35	STK35	100.0	100
STK36	STK36	100.0	100
STK39	STK39	88.0	100
SYK	SYK	93.0	100
MAP3K7	TAK1	94.0	100
TAOK1	TAOK1	88.0	100
TAOK2	TAOK2	91.0	100
TAOK3	TAOK3	83.0	100
TBK1	TBK1	75.0	100
TEC	TEC	94.0	100
TESK1	TESK1	93.0	100
TGFBR1	TGFBR1	84.0	100
TGFBR2	TGFBR2	91.0	100
TIE1	TIE1	100.0	100
TEK	TIE2	92.0	100
TLK1	TLK1	72.0	100
TLK2	TLK2	89.0	100
TNIK	TNIK	100.0	100
TNK1	TNK1	100.0	100
TNK2	TNK2	70.0	100
TNNI3K	TNNI3K	89.0	100
NTRK1	TRKA	100.0	100
NTRK2	TRKB	87.0	100
NTRK3	TRKC	88.0	100
TRPM6	TRPM6	100.0	100
TSSK1B	TSSK1B	94.0	100
TSSK3	TSSK3	93.0	100
TTK	TTK	91.0	100
TXK	TXK	91.0	100
TYK2	TYK2(JH2domain-pseudokinase)	86.0	100
TYRO3	TYRO3	83.0	100
ULK1	ULK1	83.0	100
ULK2	ULK2	100.0	100
ULK3	ULK3	100.0	100
KDR	VEGFR2	96.0	100
PIK3C3	VPS34	100.0	100
VRK2	VRK2	76.0	100
WEE1	WEE1	100.0	100
WEE2	WEE2	97.0	100
WNK1	WNK1	99.0	100
WNK2	WNK2	100.0	100
WNK3	WNK3	85.0	100
WNK4	WNK4	80.0	100
STK32A	YANK1	81.0	100
STK32B	YANK2	93.0	100
STK32C	YANK3	85.0	100
YES1	YES	88.0	100
STK25	YSK1	100.0	100
MAP3K19	YSK4	71.0	100
MAP3K20	ZAK	79.0	100
ZAP70	ZAP70	100.0	100

SR-301

HGNC target name	DiscoverX gene symbol of kinase	% Control	Compound Concentration [nM]
AAK1	AAK1	90.0	100
ABL1	ABL1-phosphorylated	82.0	100
ABL2	ABL2	100.0	100
ACVR1	ACVR1	88.0	100
ACVR1B	ACVR1B	94.0	100
ACVR2A	ACVR2A	68.0	100
ACVR2B	ACVR2B	83.0	100
ACVRL1	ACVRL1	97.0	100
COQ8A	ADCK3	97.0	100
COQ8B	ADCK4	100.0	100
AKT1	AKT1	100.0	100
AKT2	AKT2	100.0	100
AKT3	AKT3	86.0	100
ALK	ALK(L1196M)	100.0	100
PRKAA1	AMPK-alpha1	100.0	100
PRKAA2	AMPK-alpha2	100.0	100
ANKK1	ANKK1	80.0	100
NUAK1	ARK5	100.0	100
MAP3K5	ASK1	100.0	100
MAP3K6	ASK2	100.0	100
AURKA	AURKA	100.0	100
AURKB	AURKB	100.0	100
AURKC	AURKC	78.0	100
AXL	AXL	79.0	100
BMP2K	BIKE	84.0	100
BLK	BLK	100.0	100
BMPR1A	BMPR1A	90.0	100
BMPR1B	BMPR1B	91.0	100
BMPR2	BMPR2	100.0	100
BMX	BMX	79.0	100
BRAF	BRAF(V600E)	100.0	100
PTK6	BRK	76.0	100
BRSK1	BRSK1	100.0	100
BRSK2	BRSK2	79.0	100
BTK	BTK	100.0	100
BUB1	BUB1	100.0	100
CAMK1	CAMK1	96.0	100
PNCK	CAMK1B	100.0	100
CAMK1D	CAMK1D	97.0	100
CAMK1G	CAMK1G	92.0	100
CAMK2A	CAMK2A	100.0	100
CAMK2B	CAMK2B	100.0	100
CAMK2D	CAMK2D	93.0	100
CAMK2G	CAMK2G	94.0	100
CAMK4	CAMK4	98.0	100
CAMKK1	CAMKK1	88.0	100
CAMKK2	CAMKK2	78.0	100
CASK	CASK	100.0	100
CDK11B	CDC2L1	100.0	100
CDK11A	CDC2L2	87.0	100
CDK13	CDC2L5	100.0	100
CDK19	CDK11	90.0	100
CDK2	CDK2	100.0	100
CDK3	CDK3	82.0	100
CDK4	CDK4-cyclinD3	100.0	100
CDK5	CDK5	94.0	100
CDK7	CDK7	100.0	100
CDK8	CDK8	100.0	100
CDK9	CDK9	87.0	100
CDKL1	CDKL1	71.0	100
CDKL2	CDKL2	100.0	100
CDKL3	CDKL3	96.0	100
CDKL5	CDKL5	100.0	100
CHEK1	CHEK1	100.0	100
CHEK2	CHEK2	100.0	100
CIT	CIT	98.0	100
CLK1	CLK1	87.0	100
CLK2	CLK2	100.0	100
CLK3	CLK3	85.0	100
CLK4	CLK4	85.0	100
CSF1R	CSF1R-autoinhibited	100.0	100
CSK	CSK	91.0	100
CSNK1A1	CSNK1A1	99.0	100
CSNK1A1L	CSNK1A1L	100.0	100
CSNK1D	CSNK1D	96.0	100
CSNK1E	CSNK1E	100.0	100
CSNK1G1	CSNK1G1	100.0	100
CSNK1G2	CSNK1G2	82.0	100
CSNK1G3	CSNK1G3	100.0	100
CSNK2A1	CSNK2A1	94.0	100
CSNK2A2	CSNK2A2	85.0	100
MATK	CTK	100.0	100
DAPK1	DAPK1	92.0	100
DAPK2	DAPK2	90.0	100
DAPK3	DAPK3	88.0	100
DCLK1	DCAMKL1	100.0	100
DCLK2	DCAMKL2	95.0	100
DCLK3	DCAMKL3	87.0	100
DDR1	DDR1	89.0	100
DDR2	DDR2	100.0	100
MAP3K12	DLK	100.0	100
DMPK	DMPK	100.0	100
CDC42BPG	DMPK2	99.0	100
STK17A	DRAK1	100.0	100
STK17B	DRAK2	100.0	100
DYRK1A	DYRK1A	87.0	100
DYRK1B	DYRK1B	100.0	100
DYRK2	DYRK2	100.0	100
EGFR	EGFR(T790M)	100.0	100
EIF2AK1	EIF2AK1	81.0	100
EPHA1	EPHA1	95.0	100
EPHA2	EPHA2	100.0	100
EPHA3	EPHA3	75.0	100
EPHA4	EPHA4	76.0	100
EPHA5	EPHA5	96.0	100
EPHA6	EPHA6	100.0	100
EPHA7	EPHA7	98.0	100
EPHA8	EPHA8	100.0	100
EPHB1	EPHB1	100.0	100
EPHB2	EPHB2	87.0	100
EPHB3	EPHB3	91.0	100
EPHB4	EPHB4	96.0	100
EPHB6	EPHB6	100.0	100
ERBB2	ERBB2	100.0	100
ERBB3	ERBB3	100.0	100
ERBB4	ERBB4	61.0	100
MAPK3	ERK1	89.0	100
MAPK1	ERK2	90.0	100
MAPK6	ERK3	94.0	100
MAPK4	ERK4	96.0	100
MAPK7	ERK5	94.0	100
MAPK15	ERK8	100.0	100
ERN1	ERN1	100.0	100
PTK2	FAK	100.0	100
FER	FER	86.0	100
FES	FES	87.0	100
FGFR1	FGFR1	91.0	100
FGFR2	FGFR2	97.0	100
FGFR3	FGFR3(G697C)	83.0	100
FGFR4	FGFR4	100.0	100
FGR	FGR	88.0	100
FLT1	FLT1	86.0	100
FLT3	FLT3-autoinhibited	97.0	100
FLT4	FLT4	81.0	100
FRK	FRK	60.0	100
FYN	FYN	56.0	100
GAK	GAK	95.0	100
EIF2AK4	GCN2(Kin.Dom.2,S808G)	100.0	100
GRK1	GRK1	94.0	100
GRK2	GRK2	72.0	100
GRK3	GRK3	100.0	100
GRK4	GRK4	100.0	100
GRK7	GRK7	100.0	100
GSK3A	GSK3A	100.0	100
GSK3B	GSK3B	100.0	100
HASPIN	HASPIN	100.0	100
HCK	HCK	100.0	100
HIPK1	HIPK1	100.0	100
HIPK2	HIPK2	100.0	100
HIPK3	HIPK3	100.0	100
HIPK4	HIPK4	100.0	100
MAP4K1	HPK1	100.0	100
HUNK	HUNK	100.0	100
CILK1	ICK	100.0	100
IGF1R	IGF1R	100.0	100
CHUK	IKK-alpha	100.0	100
IKBKB	IKK-beta	100.0	100
IKBKE	IKK-epsilon	73.0	100
INSR	INSR	100.0	100
INSRR	INSRR	100.0	100
IRAK1	IRAK1	100.0	100
IRAK3	IRAK3	100.0	100
IRAK4	IRAK4	100.0	100
ITK	ITK	100.0	100
JAK1	JAK1(JH2domain-pseudokinase)	89.0	100
JAK2	JAK2(JH1domain-catalytic)	100.0	100
JAK3	JAK3(JH1domain-catalytic)	100.0	100
MAPK8	JNK1	85.0	100
MAPK9	JNK2	83.0	100
MAPK10	JNK3	100.0	100
KIT	KIT-autoinhibited	100.0	100
LATS1	LATS1	100.0	100
LATS2	LATS2	100.0	100
LCK	LCK	100.0	100
LIMK1	LIMK1	100.0	100
LIMK2	LIMK2	100.0	100
STK11	LKB1	100.0	100
STK10	LOK	100.0	100
LRRK2	LRRK2(G2019S)	100.0	100
LTK	LTK	100.0	100
LYN	LYN	96.0	100
MAP3K13	LZK	100.0	100
MAK	MAK	100.0	100
MAP3K1	MAP3K1	81.0	100
MAP3K15	MAP3K15	74.0	100
MAP3K2	MAP3K2	100.0	100
MAP3K3	MAP3K3	100.0	100
MAP3K4	MAP3K4	75.0	100
MAP4K2	MAP4K2	100.0	100
MAP4K3	MAP4K3	75.0	100
MAP4K4	MAP4K4	66.0	100
MAP4K5	MAP4K5	76.0	100
MAPKAPK2	MAPKAPK2	100.0	100
MAPKAPK5	MAPKAPK5	100.0	100
MARK1	MARK1	74.0	100
MARK2	MARK2	100.0	100
MARK3	MARK3	100.0	100
MARK4	MARK4	71.0	100
MAST1	MAST1	100.0	100
MAP2K1	MEK1	100.0	100
MAP2K2	MEK2	90.0	100
MAP2K3	MEK3	85.0	100
MAP2K4	MEK4	100.0	100
MAP2K5	MEK5	100.0	100
MAP2K6	MEK6	67.0	100
MELK	MELK	100.0	100
MERTK	MERTK	91.0	100
MET	MET(Y1235D)	98.0	100
MINK1	MINK	85.0	100
MAP2K7	MKK7	100.0	100
MKNK1	MKNK1	86.0	100
MKNK2	MKNK2	100.0	100
MYLK3	MLCK	100.0	100
MAP3K9	MLK1	90.0	100
MAP3K10	MLK2	73.0	100
MAP3K11	MLK3	92.0	100
CDC42BPA	MRCKA	100.0	100
CDC42BPB	MRCKB	90.0	100
STK4	MST1	100.0	100
MST1R	MST1R	97.0	100
STK3	MST2	95.0	100
STK24	MST3	100.0	100
STK26	MST4	92.0	100
MTOR	MTOR	100.0	100
MUSK	MUSK	100.0	100
MYLK	MYLK	100.0	100
MYLK2	MYLK2	90.0	100
MYLK4	MYLK4	100.0	100
MYO3A	MYO3A	97.0	100
MYO3B	MYO3B	100.0	100
STK38	NDR1	83.0	100
STK38L	NDR2	24.0	100
NEK1	NEK1	51.0	100
NEK10	NEK10	100.0	100
NEK11	NEK11	100.0	100
NEK2	NEK2	100.0	100
NEK3	NEK3	100.0	100
NEK4	NEK4	100.0	100
NEK5	NEK5	95.0	100
NEK6	NEK6	86.0	100
NEK7	NEK7	88.0	100
NEK9	NEK9	100.0	100
MAP3K14	NIK	83.0	100
NIM1K	NIM1	60.0	100
NLK	NLK	100.0	100
OXSR1	OSR1	100.0	100
MAPK14	p38-alpha	100.0	100
MAPK11	p38-beta	100.0	100
MAPK13	p38-delta	100.0	100
MAPK12	p38-gamma	100.0	100
PAK1	PAK1	100.0	100
PAK2	PAK2	100.0	100
PAK3	PAK3	100.0	100
PAK4	PAK4	100.0	100
PAK6	PAK6	100.0	100
PAK5	PAK7	100.0	100
CDK16	PCTK1	100.0	100
CDK17	PCTK2	86.0	100
CDK18	PCTK3	100.0	100
PDGFRA	PDGFRA	91.0	100
PDGFRB	PDGFRB	86.0	100
PDPK1	PDPK1	99.0	100
CDPK1	PFCDPK1(P.falciparum)	100.0	100
PK5	PFPK5(P.falciparum)	100.0	100
CDK15	PFTAIRE2	74.0	100
CDK14	PFTK1	100.0	100
PHKG1	PHKG1	87.0	100
PHKG2	PHKG2	100.0	100
PIK3C2B	PIK3C2B	95.0	100
PIK3C2G	PIK3C2G	81.0	100
PIK3CA	PIK3CA(Q546K)	60.0	100
PIK3CB	PIK3CB	81.0	100
PIK3CD	PIK3CD	91.0	100
PIK3CG	PIK3CG	85.0	100
PI4KB	PIK4CB	100.0	100
PIKFYVE	PIKFYVE	61.0	100
PIM1	PIM1	95.0	100
PIM2	PIM2	88.0	100
PIM3	PIM3	100.0	100
PIP5K1A	PIP5K1A	100.0	100
PIP5K1C	PIP5K1C	85.0	100
PIP4K2B	PIP5K2B	100.0	100
PIP4K2C	PIP5K2C	100.0	100
PRKACA	PKAC-alpha	100.0	100
PRKACB	PKAC-beta	92.0	100
PKMYT1	PKMYT1	74.0	100
PKN1	PKN1	98.0	100
PKN2	PKN2	95.0	100
PKNB	PKNB(M.tuberculosis)	90.0	100
PLK1	PLK1	80.0	100
PLK2	PLK2	99.0	100
PLK3	PLK3	100.0	100
PLK4	PLK4	82.0	100
PRKCD	PRKCD	80.0	100
PRKCE	PRKCE	63.0	100
PRKCH	PRKCH	79.0	100
PRKCI	PRKCI	100.0	100
PRKCQ	PRKCQ	90.0	100
PRKD1	PRKD1	91.0	100
PRKD2	PRKD2	92.0	100
PRKD3	PRKD3	100.0	100
PRKG1	PRKG1	95.0	100
PRKG2	PRKG2	79.0	100
EIF2AK2	PRKR	55.0	100
PRKX	PRKX	100.0	100
PRPF4B	PRP4	60.0	100
PTK2B	PYK2	94.0	100
SIK3	QSK	78.0	100
RAF1	RAF1	70.0	100
RET	RET(V804M)	82.0	100
RIOK1	RIOK1	54.0	100
RIOK2	RIOK2	99.0	100
RIOK3	RIOK3	88.0	100
RIPK1	RIPK1	94.0	100
RIPK2	RIPK2	59.0	100
RIPK4	RIPK4	100.0	100
DSTYK	RIPK5	80.0	100
ROCK1	ROCK1	93.0	100
ROCK2	ROCK2	100.0	100
ROS1	ROS1	91.0	100
RPS6KA4	RPS6KA4(Kin.Dom.2-C-terminal)	91.0	100
RPS6KA5	RPS6KA5(Kin.Dom.2-C-terminal)	95.0	100
RPS6KA1	RSK1(Kin.Dom.2-C-terminal)	100.0	100
RPS6KA3	RSK2(Kin.Dom.2-C-terminal)	100.0	100
RPS6KA2	RSK3(Kin.Dom.2-C-terminal)	100.0	100
RPS6KA6	RSK4(Kin.Dom.2-C-terminal)	100.0	100
RPS6KB1	S6K1	100.0	100
SBK1	SBK1	82.0	100
SGK1	SGK	100.0	100
SBK3	SgK110	100.0	100
SGK2	SGK2	100.0	100
SGK3	SGK3	83.0	100
SIK1	SIK	100.0	100
SIK2	SIK2	86.0	100
SLK	SLK	100.0	100
NUAK2	SNARK	100.0	100
SNRK	SNRK	81.0	100
SRC	SRC	94.0	100
SRMS	SRMS	98.0	100
SRPK1	SRPK1	78.0	100
SRPK2	SRPK2	34.0	100
SRPK3	SRPK3	100.0	100
STK16	STK16	100.0	100
STK33	STK33	84.0	100
STK35	STK35	100.0	100
STK36	STK36	97.0	100
STK39	STK39	100.0	100
SYK	SYK	88.0	100
MAP3K7	TAK1	100.0	100
TAOK1	TAOK1	100.0	100
TAOK2	TAOK2	93.0	100
TAOK3	TAOK3	100.0	100
TBK1	TBK1	88.0	100
TEC	TEC	100.0	100
TESK1	TESK1	100.0	100
TGFBR1	TGFBR1	100.0	100
TGFBR2	TGFBR2	93.0	100
TIE1	TIE1	100.0	100
TEK	TIE2	73.0	100
TLK1	TLK1	94.0	100
TLK2	TLK2	82.0	100
TNIK	TNIK	45.0	100
TNK1	TNK1	96.0	100
TNK2	TNK2	91.0	100
TNNI3K	TNNI3K	63.0	100
NTRK1	TRKA	100.0	100
NTRK2	TRKB	100.0	100
NTRK3	TRKC	86.0	100
TRPM6	TRPM6	96.0	100
TSSK1B	TSSK1B	85.0	100
TSSK3	TSSK3	100.0	100
TTK	TTK	91.0	100
TXK	TXK	77.0	100
TYK2	TYK2(JH2domain-pseudokinase)	100.0	100
TYRO3	TYRO3	90.0	100
ULK1	ULK1	100.0	100
ULK2	ULK2	100.0	100
ULK3	ULK3	99.0	100
KDR	VEGFR2	85.0	100
PIK3C3	VPS34	100.0	100
VRK2	VRK2	91.0	100
WEE1	WEE1	72.0	100
WEE2	WEE2	100.0	100
WNK1	WNK1	100.0	100
WNK2	WNK2	100.0	100
WNK3	WNK3	85.0	100
WNK4	WNK4	100.0	100
STK32A	YANK1	57.0	100
STK32B	YANK2	65.0	100
STK32C	YANK3	100.0	100
YES1	YES	98.0	100
STK25	YSK1	90.0	100
MAP3K19	YSK4	92.0	100
MAP3K20	ZAK	89.0	100
ZAP70	ZAP70	100.0	100

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Selectivity data for probe SR-302 and control SR-301

PDSP data

SR-302

DiscoverX KinomeScan data

SR-302

SR-301