Physicochemical properties of probe VZ185 and control cisVZ185
| VZ185 | |
|---|---|
| CHI log D (pH 7.4) | 2.3 |
| CLogP calculated | 5.0 |
| TPSA | 177.9 Å2 |
| cisVZ185 | |
|---|---|
| CHI log D (pH 7.4) | 2.4 |
| CLogP calculated | 5.0 |
| TPSA | 177.9 Å2 |
Solubility
| VZ185: |
Aqueous Solubility (kinetic): 85 µM
|
| cisVZ185: |
Aqueous Solubility (kinetic): 79 µM
|