Usage recommendations for probe A-1211212 and control A-1210227
In cells
Use at concentration up to 5 µM.
Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.
In vivo
Use probe at 50 mkd for oral dosing once a day. A protocol for the formulation of the probe is included in the additional probe information pdf that can be downloaded from the "Probe overview tab". Note: The control has not been characterized for in vivo use.