In cells

Use at concentration of 100 nM.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in vivo in rats and mice with i.v. dose 10 mg/kg, p.o. dose 40 mg/kg (fed male), p.o. dose 10 mg/kg (fasted male)