In cells

Use at concentrations up to 10 µM. We recommend to test at various concentrations with a 9 point curve starting from 10 µM down in 1/3 serial dilutions.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

No. Use GSK778 for in vivo studies.