In cells

Use at a concentration up to 1 µM.

No significant toxicity in A549 cells incubated with JYQ-173 up to 5 µM for 72h (renewed after 36h; Cell Titer Blue assay). Good cell permeability shown.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Not tested in vivo.