Potency data for probe BAY-1797 and control BAY-207
No in vitro potency data available.
In cell potency
| Target name | Target information | Species | Assay description | BAY-1797 | BAY-207 | Publication of assay conditions |
|---|---|---|---|---|---|---|
| P2RX4 | HEK293 cells stably expressing human P2RX4 | Homo sapiens | Fluorometric imaging plate reader (FLIPR)-based Ca2+ assay with HEK293 cells | IC50 = 211 nM | IC50 = 25 µM | PMID: 31746599 |
| P2RX4 | 1321 N1 Astrocytoma cells stably expressing human P2RX4 | Homo sapiens | Fluorometric imaging plate reader (FLIPR)-based Ca2+ assay with 1321 N1 Astrocytoma cells | IC50 = 108 nM | PMID: 31746599 | |
| P2RX4 | HEK293 cells stably expressing human P2RX4 | Homo sapiens | Ephys Qpatch Assay with HEK293 cells | IC50 = 274 nM | PMID: 31746599 | |
| P2RX4 | 1321 N1 Astrocytoma cells stably expressing human P2RX4 | Homo sapiens | Ephys Qpatch Assay with 1321 N1 Astrocytoma cells | IC50 = 320 nM | PMID: 31746599 |