Potency data for probe BAY-784 and control BAY-786
In vitro potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| GNRHR | Homo sapiens | Binding assay (Tag Lite) | IC50 = 27 nM |
In cell potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| GNRHR | CHO cells stably expressing GNRHR | Homo sapiens | Mechanistic assay measuring cellular IP1 : Buserelin at ~EC80 | IC50 = 21 nM | ||
| GNRHR | CHO cells stably expressing GNRHR | Homo sapiens | Mechanistic assay measuring cellular IP1 : Buserelin at ~EC80 | IC50 = 2.400 µM (n=7) |