Potency data for probe BAY-876 and control BAY-588
No in vitro potency data available.
In cell potency
| Target name | Target information | Species | Assay description | BAY-876 | BAY-588 | Publication of assay conditions |
|---|---|---|---|---|---|---|
| SLC2A1 | Homo sapiens | Cell-based assay with CellTiter-Glo readout for ATP production with SLC2A1 | IC50 = 2 nM | IC50 = 1.2 µM | PMID: 27552707 | |
| SLC2A4 | Homo sapiens | Cell-based assay with CellTiter-Glo readout for ATP production with SLC2A4 | IC50 = 0.27 µM | IC50 = 0.5 µM | PMID: 27552707 | |
| SLC2A2 | Homo sapiens | Cell-based assay with CellTiter-Glo readout for ATP production with SLC2A2 | IC50 = 9.4 µM | IC50 > 10 µM | PMID: 27552707 | |
| SLC2A3 | Homo sapiens | Cell-based assay with CellTiter-Glo readout for ATP production with SLC2A3 | IC50 = 1.6 µM | IC50 = 5.5 µM | PMID: 27552707 | |
| SLC2A1, MAPK7 | Homo sapiens | Cellular mechanistic assay: Inhibition of glucose uptake by Hela-MaTu cells | IC50 = 3.2 nM | PMID: 30563338 |