Potency data for probe BI-2081 and control BI-0340
In vitro potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| FFAR1 | Homo sapiens | FFAR1 biochemical assay | Ki = 23 nM |
In cell potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| FFAR1 | 1321N1 cells expressing human FFAR1 | Homo sapiens | IPOne assay: Stimulation of 1321N1 cells followed by measurement of the IP1 accumulation by fluorescence | EC50 = 3 nM | EC50 = 1230 nM |