Potency data for probe TP-021 and control TP-021n
In vitro potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| BCL6 | Homo sapiens | Cell-free enzyme-linked immunosorbent assay (ELISA) | IC50 = 100 nM | IC50 = 110 µM | PMID: 28760529 |
In cell potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| BCL6 | HEK293T cells; full-length | Homo sapiens | Cell-based mammalian two-hybrid (M2H) assay | IC50 = 720 nM | PMID: 28760529 |