In cells

Use at concentration from 1 to 10 μM

We recommend to use the the two BCL6 degrader, CCT369260 and BI-3802, and the BCL6 inhibitor BI-3812 also available from SGC for control experiments.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Mouse 1 mg/kg po, 0.1 mg/kg iv