Physicochemical properties of JNJ-8003
| JNJ-8003 | |
|---|---|
| Melting point | 168 °C |
| Polar surface area (PSA) | 118.0 |
| log D | 3.6 |
| cLogP | 4.0 |
| Ligand efficiency (LE) | 0.3 |
| Ligand-lipophilicity efficiency (LLE) | 5.2 |
Solubility
| JNJ-8003: |
Aqueous pH 2: 22 mM,
Aqueous pH 4: <0.9 mM,
FASSIF: 143 mM,
FESSIF: 220 mM
|