Physicochemical properties of probe MLi-2 and control MLi-2-NC
| MLi-2 | |
|---|---|
| HPLC Log D (pH 7.5) | 3.6 |
| MLi-2-NC | |
|---|---|
| HPLC Log D (pH 7.5) | 4.2 |
Solubility
| MLi-2: |
PBS pH 2: 153 µM,
PBS pH 6.5 FASSIF: 24 µM,
DMSO: >= 26 mg/mL,
PBS pH 7.0: Below limit of quantitation
|
| MLi-2-NC: |
PBS pH 2: 183 µM,
PBS pH 6.5 FASSIF: 134 µM,
PBS pH 7.0: 7 µM
|