In cells

The selectivity over SLC9A2 is 30-fold and therefore we recommend to only use concentrations of up to 5 µM for in vitro experiments. Use together with control at highest dose of probe.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in rat and dogs with 1 mg/kg (iv).