In cells

Use at concentration < 300 nM.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in mice (0.1 -10 mg/k (po)) and rats (1 - 10 mg/kg (po)). A significant effect was shown in the isogenic mouse model of endometriosis.