Potency data for probe A-446 and control A-426
In vitro potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| GLS | Homo sapiens | GLS Enzyme activity assay | IC50 = 31 nM | IC50 > 30 µM | ||
| GLS2 | Homo sapiens | GLS2 Enzyme activity assay | IC50 > 30 µM | IC50 > 30 µM |
In cell potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| Homo sapiens | A549 CTG Assay | IC50 = 10.500 nM |