Potency data for probe BAY-3153 and control BAY-173
No in vitro potency data available.
In cell potency
| Target name | Target information | Species | Assay description | BAY-3153 | BAY-173 | Publication of assay conditions |
|---|---|---|---|---|---|---|
| CCR1, CCR2 | Calcium-optimized stable cell line, #HTS005C | Homo sapiens | CCR1 cellular Ca2+-flux assay: Calcium transients are detected by Fluo8 Ca-sensitive dye | IC50 = 3 nM | IC50 = 1.2 µM | Slide 13 in BAY-3153 Antagonist for CCR1.pdf |