Potency data for probe BAY-707 and control BAY-604
In vitro potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| NUDT1 | full-length human | Homo sapiens | PPiLight Biochemical Assay | IC50 = 2.300 nM ± 0.800 nM (n=6) | IC50 > 20 µM | PMID: 29485874 |
In cell potency
| Target name | Target information | Species | Assay description | Probe result (SD) | Control result (SD) | Publication of assay conditions |
|---|---|---|---|---|---|---|
| NUDT1 | K 562 cells | Homo sapiens | Cellular Thermal Shift Assay (CETSA) | EC50 = 7.600 nM | PMID: 29485874 |