Potency data for probe KISS1-305 and control KISS1-543
In vitro potency
| Target name | Target information | Species | Assay description | KISS1-305 | KISS1-543 | Publication of assay conditions |
|---|---|---|---|---|---|---|
| KISS1R | Homo sapiens | Cell free activity assay: Binding to human GPR54 | Ki = 0.089 nM |
In cell potency
| Target name | Target information | Species | Assay description | KISS1-305 | KISS1-543 | Publication of assay conditions |
|---|---|---|---|---|---|---|
| KISS1R | Homo sapiens | Cellular activity assay: GPR54 expressing cell growth | IC50 = 8.94 nM | |||
| KISS1R | Homo sapiens | Agonist activity for hGPR54 (C-terminal ethyl amide) | EC50 > 1 µM |