In cells

Use between 1 nM and 1 µM.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in rat. KISS-305 shows robust efficacy in inducing ovulation in rat models (30 nM/kg) and activating GnRH neurons.