Physicochemical properties of probe BAY 1753011 and control BAY-2297
| BAY 1753011 | |
|---|---|
| TPSA | 107.8 Å2 |
| Stability pH 1/ 7/ 10, 7days at RT | all 100 % |
| log D (pH 7.5) | 3.1 |
| BAY-2297 | |
|---|---|
| TPSA | 73.96 Å2 |
| Stability pH 1/ 7/ 10, 24 h, 37°C | 100%/ 100%/ 99% |
| log D (pH 7.5) | 2.7 |
Solubility
| BAY 1753011: |
aqueous solution pH 7.4 (cryst. material): 108 g/L
|
| BAY-2297: |
aqueous solution pH 7.4 (cryst. material): 263 g/L
|