Physicochemical properties of probe BI-5524 and control BI-5525
| BI-5524 | |
|---|---|
| log P | 2.7 |
| BI-5525 | |
|---|---|
| log P | 2.7 |
Solubility
| BI-5524: |
HT pH 6.8: 79 µg/mL,
HT pH 4.5: 75 µg/mL,
SF pH 6.8: 30 µg/mL,
SF pH 4.5: 30 µg/mL,
10 % 2-hydroxylpropyl-β-cyclodextrin (HP-β-CD): 2300 µg/mL
|
| BI-5525: |
Aqueous pH 6.8: 79 µg/mL
|