In cells

Use at concentration of 100 nM.

We recommend to use together with the ELANE inhibitor BAY-678 also available from SGC for control experiments.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in mouse and rat with with 1-10 µM/kg