Physicochemical properties of probe PFI-653 and control PFI-653-N
| PFI-653 | |
|---|---|
| Exp. log D (octanol/buffer shake flask method) | -0.1 |
| LipE | 8.2 |
| PFI-653-N | |
|---|---|
| Exp. log D (octanol/buffer shake flask method) | 0.1 |
Solubility
| PFI-653: |
Kinetic solubility (pH 6.5): 599 µM, 
Thermodynamic solubility (pH 7.4): 8.1 mg/mL
|
| PFI-653-N: |
Kinetic solubility (pH 6.5): 441 µM
|