Usage recommendations for probe PFI-653 and control PFI-653-N
In cells
Use at concentration up to 1 µM.
Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.
In vivo
Tested in rat with 2 mg/kg i.v. dose and 10 mg/kg p.o. dose.