Physicochemical properties of probe WEB2086 and control WEB2387
| WEB2086 | |
|---|---|
| log P | 1.0 |
| WEB2387 | |
|---|---|
| log P | 0.9 |
Solubility
| WEB2086: |
HT pH 6.8: > 100 µg/mL (amorph),
HT pHc4.5: > 105 µg/mL (amorph),
McIlvaine buffer pH 6.8: 4000 µg/mL (cryst.),
McIlvaine buffer pH 4.5: 2600 µg/mL (cryst.),
10% HP b CD: 2300 µg/mL (amorph)
|
| WEB2387: |
HT pH 6.8: 86 µg/mL
|