Usage recommendations for probe ABT-100 and control A-108
In cells
Effective concentration range: 0.01 - 1000 nM
Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.
In vivo
ABT-100 shows an effect on the growth of DLD-1 colon carcinoma in nude mice with a dose of 6.25-25 mg/kg/day s.c. for 21 days.