In cells

Use at a concentration of 100 nM in cell-based experiments. Doses > 1 µM are not recommended to be employed in any experiments.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in rat with a dose of 1 - 30 mg/kg (po) and dog.