Usage recommendations for probe Skepinone-L and control FM-743
In cells
Use at concentration of 1 µM.
The MAPK14 probes, FS-694 and SR-318, available from this website can be used as additional control to dissect MPAK14 activity further.
Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.
In vivo
Tested in mice with 3 mg/kg p.o.