In cells

Use at 1 µM in cellular systems; no general cell toxicity up to 10 µM.

We recommend to use the Dopamine Receptor D4 agonist probe ABT-724 also available from SGC for control experiments.

Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.

In vivo

Tested in mice: Single IP administration at 10 mg/kg dose; poor brain penetrance.