Usage recommendations for probe BI-3812 and control BI-5273
In cells
Use at concentration up to 1 µM.
We recommend to use together with the BCL6 degraders CCT369260 and BI-3802 and the BCL6 inhibitor TP-021 also available from SGC for control experiments. Note: BI-3812 is soluble in DMSO only to a concentration of 1 mM.
Use the recommended concentration to avoid off-target toxicity and/or off-target activity. Using concentrations that are higher than recommended could lead to false positive or confounding results.
In vivo
Not tested in vivo.